Research progress on the roles of angiopoietin-like protein 8 in the pathogenesis of cardiovascular diseases
10.16352/j.issn.1001-6325.2024.04.0544
- VernacularTitle:血管生成素样蛋白8在心血管疾病发病中作用的研究进展
- Author:
Lijie HAN
1
;
Chaowei HU
;
Huahui YU
;
Yanwen QIN
Author Information
1. 首都医科大学附属北京安贞医院 心血管重塑相关疾病教育部重点实验室,北京 100029
- Keywords:
angiopoietin-like protein 8;
coronary artery disease;
hypertension;
aortic aneurysm;
pathological cardiac hypertrophy
- From:
Basic & Clinical Medicine
2024;44(4):544-547
- CountryChina
- Language:Chinese
-
Abstract:
Angiopoietin-like protein 8(ANGPTL8)secreted by liver and adipose tissue,is a glycoprotein exerting paramount effects on facilitation of vascular remodeling and regulation of inflammatory response;ANGPTL8 is in-volved in the initiation and progression of cardiovascular diseases including coronary artery disease,hypertension,aortic aneurysm and pathological cardiac hypertrophy,and holds promise for being a new target for the prevention and treatment of cardiovascular diseases.
