Procoagulant activity and thrombelastography in korean hemorrhagic fever.
- Author:
Munho LEE
1
;
Seonyang PARK
;
Jin Suk HAN
;
Young Yiul LEE
;
Hyok Yop LEE
;
Kyung Chae KYE
;
Byoung Kook KIM
;
Jung Sang LEE
Author Information
- Publication Type:Original Article ; Research Support, Non-U.S. Gov't
- Keywords: Korean hemorrhagic fever; thrombelastography (TEG); procoagulant activity
- MeSH: Adult; Blood Coagulation; Blood Coagulation Factors/*analysis; Hemorrhagic Fever with Renal Syndrome/*blood; Humans; Male; *Thrombelastography
- From:Journal of Korean Medical Science 1986;1(1):53-58
- CountryRepublic of Korea
- Language:English
- Abstract: Twenty male patients with Korean hemorrhagic fever were evaluated with thrombelastography (TEG) to assess the changes in coagulation system, and the results were compared with those of conventional coagulation tests. Procoagulant activity in the plasma was determined by comparing the reaction time "r" of the normal plasma and that of the mixture of equal parts of the normal plasma and the patient's plasma. The TEG was found to be a useful measure of the changes in the coagulation profile, and provided instant accurate assessment of the patient's hemostatic function. Presence of the procoagulant activity was demonstrated in the plasma of the patients and indicated occurrence of active intravascular coagulation during the early stage of the disease.
