Effects of different radiation doses on the accuracy of quantitative iodine concentration and CT value of virtual monochromatic image in second-generation dual-layer detector spectral CT
10.16352/j.issn.1001-6325.2023.12.1866
- VernacularTitle:辐射剂量对第二代双层探测器光谱CT碘定量和单能量图像CT值准确性的影响
- Author:
Qiaoling WU
1
;
Junping TIAN
;
Daming ZHANG
;
Zhengyu JIN
;
Xiaomei LU
;
Shenghui YU
;
Yun WANG
Author Information
1. 中国医学科学院 北京协和医学院 北京协和医院 放射科,北京 100730
- Keywords:
spectral CT;
iodine quantification;
radiation dose
- From:
Basic & Clinical Medicine
2023;43(12):1866-1870
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of different radiation doses on the accuracy of iodine quantification and CT value of virtual monochromatic image with a muti-spectral CT iodine phantom using second-generation dual-layer detector spectral CT(DLCT).Methods The second-generation DLCT scan abdominal phantom was used,which consisted of six different concentrations of iodine rods at 4,8 and 12 g/L.The scan parameters were set at 100,120 and 140 kVp tube voltages,and six radiation exposure sequences were scanned at each tube voltage:5,10,15,20,25 and 30 mGy.Measure the iodine concentration value and the CT value at the single level of 50,70 and 100 keV,and calculate the absolute error value of iodine concentration and CT value under different radiation exposure.SPSS 22.0 software single factor analysis of variance was used to compare the difference between the io-dine concentration and the absolute error of CT value under different Radiation exposure,and LSD method was used to compare the two groups.Results The absolute error of CT value of 4 g/L iodine rod with 10～30 mGy scanning at 100 keV energy level was significantly higher than that of 12 g/L and 8 g/L(P＜0.05),and the absolute error of iodine concentration measurement of other iodine rods with different concentrations at different Radiation exposure had no statistical difference.Conclusions The second-generation double-layer detector spectral CT has high meas-urement stability for iodine concentration quantification and CT value accuracy under conditions of radiation dose greater than 5 mGy.
