Technical guideline for intra-prepontine cisternal drug delivery via spinal puncture through subarachnoid catheterization
10.11817/j.issn.1672-7347.2024.230597
- VernacularTitle:经脊柱椎间隙穿刺蛛网膜下腔脑桥前池置管药物输注技术应用指南
- Author:
Xinning LI
1
,
2
;
Yaping WANG
;
Dingquan ZOU
;
Wei ZHANG
;
Xin LI
;
Peiyao HE
;
Haocheng ZHOU
;
Tongbiao YANG
;
Jun ZHU
;
Bo HONG
;
Yu ZHANG
;
Yanying XIAO
Author Information
1. 中南大学湘雅二医院疼痛科,长沙 410011
2. 湖南省疼痛临床医学研究中心,长沙 410011
- Keywords:
intrathecal drug delivery;
prepontine cistern;
cancer pain;
neuropathic pain;
refractory pain;
craniofacial pain;
modified Delphi
- From:
Journal of Central South University(Medical Sciences)
2024;49(1):1-10
- CountryChina
- Language:Chinese
-
Abstract:
Objective:The distribution characteristics of intrathecal drugs and the limitation of current catheterization techniques make traditional intrathecal analgesic treatment nearly useless for refractory craniofacial pain,such as trigemina neuralgia.This technical guideline aims to promote the widespread and standardize the application of intra-prepontine cisternal drug delivery via spinal puncture and catheterization. Methods:A modified Delphi approach was used to work for this guideline.On the issues related to the intra-prepontine cisternal targeted drug delivery technique,the working group consulted 10 experts from the field with 3 rounds of email feedback and 3 rounds of conference discussion. Results:For the efficacy and safety of the intra-prepontine cisternal targeted drug delivery technique,a consensus was formed on 7 topics(with an agreement rate of more than 80%),including the principles of the technique,indications and contraindications,patient preparation,surgical specifications for intra-prepontine cisternal catheter placement,analgesic dosage coordination,analgesic management,and prevention and treatment of complications. Conclusion:Utilizing the intra-prepontine cisternal drug infusion system to manage refractory craniofacial pain could provide advantages in terms of minimally invasive,secure,and effective treatment.This application can not only alleviate the suffering of individuals experiencing the prolonged pain but also support the maintenance of quality of life and dignity in their final moments,justifiing its widespread dissemination and standardized adoption in domestic and international professional fields.
