A case of hyperparathyroidism secondary to tumor-induced osteomalacia
10.11817/j.issn.1672-7347.2023.220547
- VernacularTitle:肿瘤性骨软化症继发甲状旁腺功能亢进症1例
- Author:
Youbo YANG
1
;
Ping JIN
;
Shuting ZHANG
;
Ke CHEN
;
Honghui HE
;
Zhaohui MO
;
Jingjing YUAN
Author Information
1. 中南大学湘雅三医院内分泌科,长沙 410013
- Keywords:
tumor-induced osteomalacia;
hyperparathyroidism;
phosphatiduric mesenchymal tumor;
fibroblast growth factor 23
- From:
Journal of Central South University(Medical Sciences)
2023;48(12):1937-1943
- CountryChina
- Language:Chinese
-
Abstract:
Tumor-induced osteomalacia(TIO)is a rare paraneoplastic syndrome in which tumor-induced osteochondrosis is a metabolic bone disease caused by increased renal excretion of phosphorus due to excessive secretion of fibroblast growth factor 23(FGF23)by tumor tissue.We report here a rare case of TIO in which the tumor was found in the hyoid body and the patient had tertiary hyperparathyroidism.The patient's symptoms did not improve after removal of the tumor from the hyoid body,and the patient's hypophosphatemia was gradually improved after subsequent removal of the left parathyroid gland.TIO derived from the tongue tumor is very rare,and also subsequent tertiary hyperparathyroidism is even rarer.This report helps to improve the understanding of TIO and provides reference in the diagnosis and treatment of TIO.
