Data Mining of Medication Rules for the Treatment of Atopic Dermatitis the Children by Chinese Medical Master XUAN Guo-Wei
10.13359/j.cnki.gzxbtcm.2024.03.033
- VernacularTitle:国医大师禤国维治疗儿童特应性皮炎用药规律的挖掘
- Author:
Jin-Dian DONG
1
;
Cheng-Cheng GE
;
Yue PEI
;
Shu-Qing XIONG
;
Jia-Fen LIANG
;
Qin LIU
;
Xiu-Mei MO
;
Hong-Yi LI
Author Information
1. 广州中医药大学第二临床医学院,广东广州 510405
- Keywords:
atopic dermatitis;
children;
clearing therapy;
supplementing therapy;
harmonizing therapy;
Saposhnikoviae Radix;
Glehniae Radix;
Perillae Folium;
medication rules;
data mining;
XUAN Guo-Wei;
Chinese medical master
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2024;41(3):752-758
- CountryChina
- Language:Chinese
-
Abstract:
Objective Data mining technology was used to mine the medication rules of the prescriptions used in the treatment of pediatric atopic dermatitis by Chinese medical master XUAN Guo-Wei.Methods The medical records of effective cases of pediatric atopic dermatitis treated by Professor XUAN Guo-Wei at outpatient clinic were collected,and then the medical data were statistically analyzed using frequency statistics,association rule analysis and cluster analysis.Results A total of 242 prescriptions were included,involving 101 Chinese medicinals.There were 23 commonly-used herbs,and the 16 high-frequency herbs(frequency＞100 times)were Glycyrrhizae Radix et Rhizoma,Saposhnikoviae Radix,Glehniae Radix,Perillae Folium,Ophiopogonis Radix,Cynanchi Paniculati Radix et Rhizoma,Microctis Folium,Dictamni Cortex,Scrophulariae Radix,Coicis Semen,Cicadae Periostracum,Lilii Bulbus,Rehmanniae Radix,Kochiae Fructus,Sclerotium Poriae Pararadicis,and Euryales Semen.The analysis of the medicinal properties showed that most of the herbs were sweet and cold,and mainly had the meridian tropism of the spleen,stomach and liver meridians.The association rule analysis yielded 24 commonly-used drug combinations and 20 association rules.Cluster analysis yielded 2 core drug combinations.Conclusion For the treatment of pediatric atopic dermatitis,Professor XUAN Guo-Wei focuses on the clearing,supplementing and harmonizing therapies,and the medication principle of"supporting the healthy-qi to eliminate the pathogen,and balancing the yin and yang"is applied throughout the treatment.
