Research Progress on the Mechanism of Acupuncture Intervention on Alzheimer's Disease

VernacularTitle:针刺干预阿尔茨海默病作用机制的研究进展
Author: Qing-Qing REN ¹ ; Xing-Fang PAN
Author Information

1. 天津中医药大学,天津 301617
Keywords: acupuncture; Alzheimer's disease; neuronal protection; axonal regeneration; mechanism; review
From: Journal of Guangzhou University of Traditional Chinese Medicine 2024;41(3):653-658
CountryChina
Language:Chinese
Abstract: Alzheimer's disease(AD)is a multi-cause neurodegenerative disease characterized by memory impairment.There have been serious obstacles to the effective treatment of AD.Acupuncture,as a component of traditional Chinese medicine,plays an important role in the treatment of AD.Acupuncture has been shown to protect neurons from degeneration and promotes axonal regeneration in neurodegenerative diseases such as AD.According to existing studies,the mechanisms of acupuncture on AD include the following aspects:modulation of Aβ metabolism,tau phosphorylation,cholinergic neurotransmitters,neuroinflammation,synaptic and neuronal function,autophagy,brain glucose metabolism,intestinal flora,and inhibition of nerve cell apoptosis,which in turn improves cognition.