Exploration on the idea of reducing the reproductive toxicity of Tripterygium wilfordii from the theory of "Yi and Gui homology" in TCM
10.3760/cma.j.cn115398-20230107-00071
- VernacularTitle:从“乙癸同源”探讨雷公藤生殖毒性的中医药减毒思路
- Author:
Zihao LI
1
;
Ke WANG
;
Baicun GUO
;
Shengyao LI
;
Mingyi WANG
;
Shanshan HAN
Author Information
1. 河南中医药大学中医学院2019级本科生，郑州 450046
- Keywords:
Tripterygium wilfordii;
Yi and Gui homology;
Homogeny of liver and kidney;
Reproductive toxicity
- From:
International Journal of Traditional Chinese Medicine
2024;46(2):151-155
- CountryChina
- Language:Chinese
-
Abstract:
Tripterygium wilfordii is widely used in the treatment of autoimmune system diseases, but its obvious reproductive toxicity limits the clinical application and promotion of the drug. At present, there is no clear solution to the reproductive injury of Tripterygium wilfordii. TCM believes that its reproductive toxicity lies in its properties of pungent, bitter, and cold. Long-term use can dry liver and blood, hurt liver and yang, consume kidney essence, damage kidney and yang, destroy the balance of qi and blood, yin and yang in the internal organs, and cause infertility. Based on the relationship between liver and kidney and human reproductive function, this article proposed to understand the reproductive toxicity of Tripterygium wilfordii from the perspective of "Yi and Gui homology", and explored the method of reducing the reproductive toxicity of Tripterygium wilfordii according to the thought of "treating liver and kidney together", in order to expand the theoretical thinking of TCM for the safe clinical application of this drug.
