Research progress in signaling pathways related to acupuncture regulation of post-stroke depression
10.3760/cma.j.cn115398-20221116-00240
- VernacularTitle:针刺调控卒中后抑郁相关信号通路研究进展
- Author:
Zexu DAI
1
;
Kaifeng HE
;
Jiejie HUANG
;
Wenting HAN
;
Lifen WANG
Author Information
1. 陕西中医药大学2021级硕士研究生,咸阳 712046
- Keywords:
Acupuncture;
Stroke;
Depression;
Signaling pathway;
Review
- From:
International Journal of Traditional Chinese Medicine
2024;46(1):129-133
- CountryChina
- Language:Chinese
-
Abstract:
The signaling pathways involved in acupuncture intervention in post-stroke depression (PSD) mainly include cAMP signaling pathway, MAPK signaling pathway, PI3K/Akt/mTOR signaling pathway, NF-κB signaling pathway, CREB signaling pathway, and CaMK signaling pathway. A variety of regulatory networks are formed between these signaling pathways, which play a key role in reducing inflammation, inhibiting apoptosis, improving neuroplasticity, promoting angiogenesis, and protecting neurons.