Clinical study of Bazheng Powder combined with traditional Chinese medicine fumigation in the treatment of Yin deficiency and damp-heat syndrome of refractory urinary tract infection
10.3760/cma.j.cn115398-20220714-00165
- VernacularTitle:八正散加减结合中药熏蒸治疗难治性尿路感染阴虚湿热证的临床研究
- Author:
Wei LIU
1
;
Jianzhong ZHANG
;
Huaiwen PENG
;
Xiaodong TAI
;
Qing XU
Author Information
1. 六安市中医院急诊科/全科医学科，六安 237006
- Keywords:
Lower urinary tract symptoms;
Recurrent urinary tract infections;
Yin deficiency and dampness heat;
Ba Zheng San;
Steaming washing therapy
- From:
International Journal of Traditional Chinese Medicine
2023;45(10):1237-1240
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the clinical efficacy of Bazheng Powder combined with Traditional Chinese Medicine (TCM) fumigation in the treatment of refractory urinary tract infection patients with Yin deficiency damp-heat syndrome.Methods:Randomized controlled trial design. Ninety-seven patients with Yin deficiency and damp-heat syndrome of refractory urinary tract infection in our hospital from April 2021 to May 2022 were selected as observation objects, and were divided into observation group (49 cases) and control group (48 cases) by random number table method. The control group was treated with antibiotics, and the observation group was treated with Bazheng powder plus or minus plus TCM fumigation on the basis of control group. Both groups were treated for 14 days. TCM syndrome score was performed before and after treatment. Test tube method was used to measure WBC, urine routine nitrite was used to measure urinary bacteria count, and the time to return to normal urine routine, symptom remission time and symptom disappearance time were recorded. Adverse reactions were recorded and clinical efficacy was evaluated.Results:The total effective rate was 95.92% (47/49) in the observation group and 81.25% (39/48) in the control group, and the difference between the two groups was statistically significant ( χ2=5.19, P=0.022). After treatment, TCM syndrome score of observation group was significantly lower than that of the control group ( t=13.18, P<0.01), WBC and urinary bacteria count were significantly lower than those in the control group ( t values were 19.77 and 22.99, P<0.01). The time of urine routine recovery, symptom remission and symptom disappearance in the observation group were significantly faster than those in the control group ( t values were 23.61, 9.80, 7.34, P<0.01). During the treatment period, the incidence of adverse reactions was 8.33% (4/48) in the control group, and no adverse reactions occurred in the observation group, the difference between the two groups was statistically significant ( χ2=4.26, P=0.039). Conclusion:The addition and reduction of Bazheng Powder combined with TCM fumigation can improve the clinical symptoms and clinical efficacy of patients with Yin deficiency damp-heat syndrome of refractory urinary tract infection, and no adverse reactions occurred.
