Management strategies for locally advanced operable esophageal carcinoma achieving clinical complete response after neoadjuvant chemoradiotherapy
10.3760/cma.j.cn371439-20230828-00140
- VernacularTitle:局部晚期可手术食管癌经新辅助放化疗达临床完全缓解后的处理策略
- Author:
Heyi GONG
1
;
Yan YI
;
Jian ZHANG
;
Baosheng LI
Author Information
1. 山东第一医科大学附属中心医院肿瘤科，济南 250013
- Keywords:
Esophageal neoplasms;
Chemoradiotherapy, adjuvant;
Wait and see;
Salvage surgery;
Systemic therapy
- From:
Journal of International Oncology
2023;50(12):745-750
- CountryChina
- Language:Chinese
-
Abstract:
The standard treatment mode for locally advanced operable esophageal carcinoma is neoadjuvant chemoradiotherapy combined with radical esophagectomy. However, considering the clinical need for organ retention, the treatment strategies for those achieving complete clinical response after neoadjuvant chemoradiotherapy include watchful waiting (omitting surgery), delayed or salvage surgery, and strengthened systemic treatment. These treatment strategies can significantly improve the quality of patients' life while ensuring local control and long-term survival. The feasibility and clinical value of these treatment strategies are deeply explored, hoping to provide new treatment ideas for this group of patients.
