Efficacy of subcutaneous negative pressure drainage device in the prevention of surgical site infections of superficial incisions in the open surgery of the lower gastrointestinal tract
10.3760/cma.j.cn115396-20230810-00026
- VernacularTitle:皮下负压引流装置预防下消化道开放手术浅表切口手术部位感染的疗效
- Author:
Yiqiao ZHANG
1
;
Wenyao ZHANG
;
Guocong WU
;
Yun YANG
;
Peixin LI
;
Guojun WANG
;
Jin WANG
;
Kai PANG
;
Zhongtao ZHANG
;
Jun LI
Author Information
1. 首都医科大学附属北京友谊医院普通外科中心 消化健康全国重点实验室 国家消化系统疾病临床医学研究中心，北京 100050
- Keywords:
Surgical procedures, operative;
Infection;
Negative-pressure wound therapy;
Lower gastrointestinal tract;
Surgical site infection;
Subcutaneous drainage de
- From:
International Journal of Surgery
2023;50(10):704-710
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the role of subcutaneous negative pressure drainage device in the prevention of surgical site infections (SSI) of superficial incisional in lower digestive tract open surgeries.Methods:Clinical data of 104 patients receiving open surgeries on lower digestive tract at Beijing Friendship Hospital, Capital Medical University from October 2018 to June 2020 was analyzed by a propensity score matching (PSM), and the clinical data of 104 patients receiving open surgeries on lower digestive tract at Beijing Friendship Hospital, Capital Medical University from February to December 2021 was analyzed by a randomized controlled trial (RCT). Chi-square tests were conducted to analyze the association of subcutaneous negative pressure drainage device with SSI of superficial incisional. Univariate and multivariate Logistic regression analysis were used to identify the risk factors for SSI in superficial incisions.Results:Patients with subcutaneous negative pressure drainage device encounter significantly less SSI of superficial incisional in both the PSM study ( P=0.007) and the RCT study ( P=0.049). In the PSM study, the independent risk factors for SSI of superficial incisional via univariate and multivariate Logistic regression analysis were absence of subcutaneous drainage ( Puni=0.012, Pmulti=0.009) and postoperative anastomosis leak ( Puni=0.054, Pmulti=0.034). In the RCT study, the independent risk factors for SSI of superficial incisional via univariate and multivariate Logistic regression analysis were absence of subcutaneous drainage ( Puni=0.061, Pmulti=0.017), eldly ( Puni=0.076, Pmulti=0.032), long incision ( Puni=0.078, Pmulti=0.040). Conclusion:Subcutaneous negative pressure drainage device can significantly reduce SSI of superficial incisional in lower digestive tract open surgeries.
