Research progress in anti-postoperative adhesion biofilm materials
10.3760/cma.j.cn121382-20231025-00604
- VernacularTitle:防术后粘连生物膜材料研究进展
- Author:
Wenlong YUAN
1
;
Jiayue HE
;
Xuemin LI
Author Information
1. 中国医学科学院 北京协和医学院生物医学工程研究所，天津 300192
- Keywords:
Adhesion;
Physical barrier;
Biofilm;
Natural polymer material;
Synthetic polymer material
- From:
International Journal of Biomedical Engineering
2023;46(6):499-505
- CountryChina
- Language:Chinese
-
Abstract:
Postoperative adhesion is a common phenomenon that occurs due to excessive inflammation and fibrin deposition during wound recovery after surgery. Postoperative adhesion can result in the adhesion of internal organs or tissues, which subsequently affects organ function and may even lead to postoperative complications. Currently, biofilm materials that prevent postoperative adhesion through physical barriers are considered the most effective strategy for managing this condition. In this paper, anti-postoperative adhesion biofilm materials derived from both natural and synthetic polymer sources are reviewed, and two emerging types of anti-adhesion biofilm materials are introduced, including nanoparticle films and drug-loaded biofilms, to provide a comprehensive reference for the future development of anti-postoperative adhesion biofilm materials.
