A case of human herpesvirus 6B encephalitis after liver transplantation and literature review

VernacularTitle:肝移植术后人类疱疹病毒6B型脑炎1例及文献复习
Author: Jian HE ¹ ; Li ZHANG ; Yisheng KANG ; Yan XIE ; Chiyi CHEN ; Wentao JIANG
Author Information

1. 天津市第一中心医院肝移植科，天津　300192
Keywords: Liver transplantation; Human herpesvirus 6B; Viral encephalitis
From: International Journal of Biomedical Engineering 2023;46(5):461-465
CountryChina
Language:Chinese
Abstract: Human herpesvirus-6 (HHV-6) is a ubiquitous virus. The incidence of HHV-6 after liver transplantation is estimated to be 22% ? 54%; it may present with fever, hepatitis, pneumonia, encephalitis, and myelosuppression and has a poor prognosis. HHV-6(+) recipients had a mortality rate of 29%, significantly higher than that of HHV-6(?) recipients (6%). Since most infections are asymptomatic, HHV-6 monitoring is not routinely performed in clinical practice, which means clinicians often ignore the diagnosis of HHV-6 and eventually delay diagnosis and treatment. In this paper, a case of human herpesvirus 6B encephalitis after liver transplantation was retrospectively analyzed, and the literature related to this disease was reviewed to improve the understanding of this disease.