Endothelial progenitor cells: potential therapeutic targets for ischemic stroke
10.3760/cma.j.issn.1673-4165.2023.12.010
- VernacularTitle:内皮祖细胞：缺血性卒中的潜在治疗靶点
- Author:
Yidian FU
1
;
Jingbo ZHANG
;
Mengyao ZHAO
;
Zhenjie TENG
;
Peiyuan LYU
Author Information
1. 河北医科大学研究生院，石家庄 050017
- Keywords:
Ischemic stroke;
Brain ischemia;
Endothelial progenitor cells;
Neovascularization, pathologic;
Neovascularization, physiologic;
Neurogenesis
- From:
International Journal of Cerebrovascular Diseases
2023;31(12):938-943
- CountryChina
- Language:Chinese
-
Abstract:
Endothelial progenitor cells (EPCs) are immature endothelial cells that can proliferate and differentiate into mature endothelial cells. After vascular injury, EPCs migrate from the bone marrow to the ischemic area, participating in damaged endothelial repair and neovascularization, providing a new potential therapeutic approach for vascular diseases including ischemic stroke. This article reviews the feasibility and limitations of EPCs as potential therapeutic targets for ischemic stroke.
