Complement system: possible intervention targets for post-stroke cognitive impairment in patients with ischemic stroke
10.3760/cma.j.issn.1673-4165.2023.11.010
- VernacularTitle:补体系统：缺血性卒中患者卒中后认知损害的可能干预靶点
- Author:
Yaxuan WU
1
;
Lingyun LIU
;
Mengfan LI
;
Xuemei LI
;
Jinbiao ZHANG
;
Zhenguang LI
Author Information
1. 潍坊医学院，潍坊 261053
- Keywords:
Stroke;
Brain ischemia;
Cognition disorders;
Complement system proteins;
Inflammation;
Neuronal plasticity;
Blood-brain barrier;
Neuroprotective agents
- From:
International Journal of Cerebrovascular Diseases
2023;31(11):857-861
- CountryChina
- Language:Chinese
-
Abstract:
Post-stroke cognitive impairment (PSCI) refers to a clinical syndrome that occurs after a stroke and meets the diagnostic criteria for cognitive impairment, lasting for more than 6 months, and seriously affecting the daily life of patients. The complement system has been confirmed to be associated with PSCI. This article reviews the correlation between complement system and PSCI, as well as the possibility of complement system as an intervention target for PSCI.
