Efficacy and safety of Tubridge flow diverter in the treatment of unruptured intracranial aneurysms
10.3760/cma.j.issn.1673-4165.2023.08.006
- VernacularTitle:Tubridge血流导向装置治疗未破裂颅内动脉瘤的有效性和安全性
- Author:
Jian LI
1
;
Jing CAI
;
Pengjie ZHANG
;
Fangdi XU
;
Yuhai LIU
;
Yang CHEN
Author Information
1. 山东第一医科大学，济南 250117
- Keywords:
Intracranial aneurysm;
Embolization, therapeutic;
Stents;
Treatment outcome
- From:
International Journal of Cerebrovascular Diseases
2023;31(8):594-599
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the efficacy and safety of Tubridge flow diverter (TFD) in the treatment of unruptured intracranial aneurysms (UIAs).Methods:The clinical data of patients with UIAs treated with TFD in the Department of Neurosurgery, Linyi People's Hospital from July 2021 to July 2023 were retrospectively analyzed. The modified Rankin Scale (mRS) was used to evaluate functional outcomes during postoperative follow-up. Digital subtraction angiography (DSA) follow-up was performed at least 3 months after procedure, and the occlusion degree of the aneurysm was assessed with the O'Kelly-Marotta (OKM) grading system.Results:A total of 52 patients (71 aneurysms) were included and 54 TFDs were successfully implanted. Forty-one patients (78.8%) were treated with TFD alone, while 11 (21.2%) were treated with TFD combined with coil embolization. One patient experienced in-stent thrombosis during the procedure, and the symptoms disappeared after medical treatment. Postoperative hemorrhage and ischemic complications occurred in each 2 cases, respectively. No patient died during the follow-up period. DSA follow-up was performed on a total of 45 aneurysms in 34 patients. The followed-up time was 8.3±3.1 months (range, 3-15 months), including 2 OKM grade A (4.4%), 11 grade B (24.4%), 1 grade C (2.2%), and 31 grade D (68.9%). At the last follow-up, 51 patients had good outcomes (mRS score 0-2), and 1 patient had poor outcome (mRS score 4).Conclusion:TFD for UIAs has a high complete occlusion rate and a low complication rate.
