Risk factors for ruptured saccular intracranial aneurysms in young adults
10.3760/cma.j.issn.1673-4165.2023.08.005
- VernacularTitle:青年人囊性颅内动脉瘤破裂的危险因素
- Author:
Maimaitiaili KUERBAN
1
;
Shilong MA
;
Wei QIN
;
Aierken SALIJIANG
;
Abudula MAIMAITITUERXUN
;
Balajiang BILALI
;
Kuerban AJIMU
;
Zhengqing LIU
Author Information
1. 喀什地区第一人民医院神经外科，喀什 844000
- Keywords:
Intracranial aneurysm;
Aneurysm, ruptured;
Risk factors;
Young adults
- From:
International Journal of Cerebrovascular Diseases
2023;31(8):590-593
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the risk factors for ruptured saccular intracranial aneurysms in young adults.Methods:Young patients with saccular intracranial aneurysm admitted to the First People's Hospital of Kashgar Region from February 2017 to November 2022 were retrospectively included. The demographic and clinical data from patients were collected. Risk factors of ruptured intracranial aneurysm were determined by univariate and multivariate regression analysis.Results:A total of 151 young patients with saccular intracranial aneurysm were enrolled, including 94 in the ruptured group (62.2%) and 57 in the unruptured group (37.8%). There were 70 males (46.4%) and 81 females (53.6%), with a median age of 41 years (interquartile range, 36-42 years). Univariate analysis showed that there were statistically significant differences in the proportion of male and triglycerides level between the ruptured group and the unruptured group (all P<0.05). Multivariate logistic regression analysis showed that males (odds ratio [ OR] 5.546, 95% confidence interval [ CI] 1.946-15.807; P=0.001), lower triglycerides ( OR 0.244, 95% CI 0.219-0.511; P<0.001), and aneurysms located in the anterior cerebral artery/anterior communicating artery ( OR 4.207, 95% CI 1.361-13.004; P=0.013) and middle cerebral artery ( OR 3.277, 95% CI 1.091-9.848; P=0.034) were the independent risk factors for intracranial aneurysm rupture. Conclusions:Male and lower triglycerides are the risk factors for ruptured saccular intracranial aneurysms in young adults. In addition, intracranial aneurysms located in the anterior cerebral artery/anterior communicating artery and middle cerebral artery are more prone to rupture.
