ADAMTS13 and ischemic stroke
10.3760/cma.j.issn.1673-4165.2023.07.012
- VernacularTitle:ADAMTS13与缺血性卒中
- Author:
Xiangyuan CHEN
1
;
Jie GAO
;
Xiangyang TIAN
Author Information
1. 南京医科大学附属淮安第一医院神经内科,淮安 223001
- Keywords:
Ischemic stroke;
ADAMTS13 protein
- From:
International Journal of Cerebrovascular Diseases
2023;31(7):551-554
- CountryChina
- Language:Chinese
-
Abstract:
Ischemic stroke can cause severe brain damage in the short term after an ischemic attack. ADAMTS13 (a disintegrin and metalloproteinase with thrombospondin type 1 motif, member 13) is a von Willbrand factor lyase that can affect both thrombosis and inflammation. It plays an important role in the occurrence, development, and outcome of ischemic stroke. In recent years, research on ADAMTS13 and ischemic stroke has gradually increased and there are some new developments. This article reviews the role of ADAMTS13 in the onset, outcome, and treatment of ischemic stroke.