Obstructive sleep apnea and vascular cognitive impairment: role of blood-brain barrier impairment
10.3760/cma.j.issn.1673-4165.2023.07.010
- VernacularTitle:阻塞性睡眠呼吸暂停与血管性认知损害：血脑屏障受损的作用
- Author:
Siyuan WANG
1
;
Zhenguang LI
;
Mengfan LI
Author Information
1. 滨州医学院第二临床医学院，烟台 264000
- Keywords:
Sleep apnea, obstructive;
Cognition disorders;
Cerebrovascular disorders;
Cerebral small vessel diseases;
Blood-brain barrier
- From:
International Journal of Cerebrovascular Diseases
2023;31(7):542-545
- CountryChina
- Language:Chinese
-
Abstract:
Obstructive sleep apnea (OSA) is a sleep disorder characterized by recurrent upper respiratory tract obstruction, sleep fragmentation, and hypoxia during sleep. This disease often leads to cognitive, emotional, and memory related neurological damage, and its mechanism is closely associated with the disruption of the blood-brain barrier (BBB). This article mainly discusses the relationship between BBB damage caused by OSA and vascular cognitive impairment (VCI), as well as the role of early prevention, intervention, and repairing BBB on reducing VCI.
