Animal models of vertebrobasilar dolichoectasia
10.3760/cma.j.issn.1673-4165.2023.06.013
- VernacularTitle:椎基底动脉延长扩张症的动物模型
- Author:
Xi LI
1
;
Huailiang ZHANG
;
Daopei ZHANG
Author Information
1. 河南中医药大学，郑州 450000
- Keywords:
Vertebrobasilar insufficiency;
Disease models, animal;
Vertebrobasilar dolichoectasia
- From:
International Journal of Cerebrovascular Diseases
2023;31(6):472-476
- CountryChina
- Language:Chinese
-
Abstract:
Vertebrobasilar dolichoectasia (VBD) is a cerebrovascular variant disease. Researches have shown that further development of VBD may lead to severe disability and even death. The pathogenesis of VBD is still unclear, and there is no specific clinical prevention and treatment scheme. Therefore, establishing a stable and reliable animal model helps to further understand the pathophysiological mechanisms and potential therapeutic targets of VBD. This article reviews the establishment methods and research progress of the available VBD animal models.
