Change of Melanocytes in Fixed Drug Eruption.
- Author:
Ai Young LEE
;
Yoo Shin LEE
- Publication Type:Original Article
- Keywords:
Fixed drug eruption;
Melanocyte;
Rete ridge
- MeSH:
Dihydroxyphenylalanine;
Drug Eruptions*;
Humans;
Melanins;
Melanocytes*;
Recurrence;
Skin
- From:Korean Journal of Dermatology
1989;27(2):171-176
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Lesional and normal skins in 10 patients of fixed drug eruption were studied. Number and vertical distance of rete ridges were measured in H & E stained specimens. Amount of free melanin and number of melanocytes were counted in dopa stained epidermal sheets. According to the number of recurrence, activity and number of melanocytes see med to be changed. The lesions of a few recurrence showed only active melano cytes, however, those of frequent recurrenoe increased number of melanocytes with marked elongation of rete ridges. It is supposed that the numerical increase of melanocytes were from the elongation of rete redges.
