A Case of Lupus Vulgaris Following BCG Vaccination.
- Author:
Dae Won GOO
;
Dae Sung LEE
;
Yung Hwan KIM
;
Won HOUH
- Publication Type:Case Report
- Keywords:
BCG vaccination;
Lupus vulgaris
- MeSH:
Child;
Dermis;
Humans;
Isoniazid;
Lupus Vulgaris*;
Male;
Mycobacterium bovis*;
Necrosis;
Shoulder;
Skin;
Tuberculosis;
Vaccination*;
Weights and Measures
- From:Korean Journal of Dermatology
1989;27(2):217-221
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We report a case of lupus vulgaris following BCG vaccination in a 12-year-old male. The patient was vaccinated against tuberculosis on right shoulder 6 months ago. The erythemstous papular eruptions began to develop on the BCG vaccinated site 2 weeks after vaccination. The eruptions progressed to be pruritic, erythematous plaque which was flat, crescent shaped, and centrally covered by adherent scales for 6 months. Histopathological findings revealed tubercles and tuberculoid structures composed of epitheloid cells and Langhans giant, cells in the dermis. Caseation necrosis within the tubercles was slight or absent. In addition, there was an infiltrate of mononuclear cells around the tubercles. The skin lesions cleared after 6 months of treatment with oral isoniazid 300mg daily.
