Application of liquid biopsy technology in early screening and diagnosis of pancreatic cancer
10.3969/j.issn.1673-4130.2023.24.022
- VernacularTitle:液体活检技术在胰腺癌早期筛查和诊断中的应用
- Author:
Yuting ZHAO
1
;
Yuchen YANG
;
Zhihui CAI
Author Information
1. 内蒙古医科大学内蒙古临床医学院,内蒙古呼和浩特 010110
- Keywords:
pancreatic cancer;
early screening;
liquid biopsy;
circulating tumor DNA;
circulating tumor cells
- From:
International Journal of Laboratory Medicine
2023;44(24):3054-3058
- CountryChina
- Language:Chinese
-
Abstract:
Pancreatic cancer is a kind of digestive system tumor with insidious clinical manifestations,rapid development and very poor prognosis,and its early diagnosis and surgical treatment can significantly improve the survival rate and prognosis of patients.So far,no tumor marker with sufficient sensitivity and specificity for early pancreatic cancer has been found for tumor screening.In recent years,more and more pancreatic canc-er-related tumor markers have been discovered and studied.Liquid biopsy has shown potential utility in a range of applications,with the advantages of non-invasive,non-destructive,real-time,multiple,and has broad prospects in many aspects of tumor diagnosis and treatment.This article discusses and summarizes the screen-ing and early diagnosis of circulating tumor cells and circulating tumor DNA in liquid biopsy,so as to provide reference for early detection and early treatment of pancreatic cancer.
