Progress on urinary microbiome and urinary tract infection in children
10.3760/cma.j.issn.1673-4408.2024.03.008
- VernacularTitle:儿童泌尿系微生物组与尿路感染的研究进展
- Author:
Mengmeng CHEN
1
;
Yi GAN
;
Danna TU
Author Information
1. 武汉科技大学医学院 430065
- Keywords:
Children;
Urinary microbiome;
Urinary tract infection;
Recurrent urinary tract infection
- From:
International Journal of Pediatrics
2024;51(3):179-182
- CountryChina
- Language:Chinese
-
Abstract:
Urine is not sterile but contains a complex urinary microbiome that is established as early as infancy and gradually refines with age. There are great differences in urinary microbiome of different ages and gender. At present，the core urinary microbiome of children has not reached a consensus. The urinary microbiome plays an important role in maintaining the integrity of urothelium，reducing the overgrowth of pathogenic bacteria，and local immune function. Changes in microbial diversity and composition are associated with various diseases of the urinary system，especially in urinary tract infections. In recent years，research on the relationship between urinary microbiome composition，microbiome，and urinary tract infection in children has been deepening. Therefore，this review aims to provide an overview of the urinary microbiome and its role in urinary tract infection in children，and to summarize the methods of intervening and reshaping the urinary microbiome in children to prevent recurrent urinary tract infections.
