Advances in anomalous aortic origin of coronary artery in children
10.3760/cma.j.issn.1673-4408.2024.02.002
- VernacularTitle:儿童冠状动脉不适窦起源研究进展
- Author:
Siqian CHEN
1
;
Mi LI
Author Information
1. 重庆医科大学附属儿童医院心内科 国家儿童健康与疾病临床医学研究中心 儿童发育疾病研究教育部重点实验室 儿科学重庆市重点实验室 400015
- Keywords:
Children;
Coronary artery;
Anomalous aortic origin;
Sudden death
- From:
International Journal of Pediatrics
2024;51(2):77-80
- CountryChina
- Language:Chinese
-
Abstract:
Anomalous aortic origin of a coronary artery（AAOCA）is a rare congenital malformation of the coronary artery，characterized by the coronary orifice origin from the inappropriate sinus of valsalva. Clinical presentations of this condition are occult，and different types present with various clinical manifestations，including exercise-induced angina，syncope，and even sudden death，particularly when the coronary artery follows an interarterial（intramural）course. Coronary computed comography angiography is an effective diagnostic method for precisely delineating the origin and shape of the coronary artery. Surgical correction is recommended upon evidence of myocardial ischemia and potential risk，and offers favorable long-term prognosis post-surgery. Despite low morbidity，limited experience in diagnosis and treatment，early diagnosis and timely treatment are of great importance because of the high potential risk related to the high-risk types. This paper aims to review the advances in the pathophysiology，clinical manifestations，diagnosis，and treatment of AAOCA to enhance recognition among pediatricians and reduce the incidence rate of sudden cardiac death in children with AAOCA.
