Progress on pathogenesis of intestinal flora and its metabolites in nonalcoholic fatty liver disease in children
10.3760/cma.j.issn.1673-4408.2023.12.010
- VernacularTitle:肠道菌群及其代谢产物在儿童非酒精性脂肪性肝病发病机制中的研究进展
- Author:
Han WANG
1
;
Yongli ZHAO
Author Information
1. 大连医科大学附属第二医院儿科 116023
- Keywords:
Children;
Nonalcoholic fatty liver disease;
Intestinal flora and its metabolites;
Treatment
- From:
International Journal of Pediatrics
2023;50(12):833-836
- CountryChina
- Language:Chinese
-
Abstract:
Nonalcoholic fatty liver disease is a common cause of chronic liver disease in children, and its incidence is increasing year by year.At present, the pathogenesis of nonalcoholic fatty liver disease is still unclear.The treatment is mainly based on non-drug treatment such as lifestyle change and weight loss, and lack of standardized and effective drug treatment.In recent years, more and more studies have confirmed the important role of intestinal flora and its metabolites in the pathogenesis of nonalcoholic fatty liver disease.But the treatment in children is still under study.Therefore, this article reviews the pathogenesis of intestinal flora and its metabolites, in order to provide new ideas and methods for clinical drug treatment in children with nonalcoholic fatty liver disease.
