Advances in vitamin K and bone metabolism in children
10.3760/cma.j.issn.1673-4408.2023.11.010
- VernacularTitle:维生素K与儿童骨代谢的研究进展
- Author:
Siting PENG
1
;
Ying LIU
Author Information
1. 湖北医药学院北京大学深圳医院培养基地儿科，十堰 442000
- Keywords:
Vitamin K;
MK-4;
MK-7;
Bone metabolism;
Osteoporosis;
Rickets
- From:
International Journal of Pediatrics
2023;50(11):759-762
- CountryChina
- Language:Chinese
-
Abstract:
Vitamin K(VK)occurs naturally in two forms, including vitamin K 1(VK 1)and vitamin K 2(VK 2). The function of VK is related to the number of its side chains.In addition to the function of coagulation, VK is also gradually found to be involved in bone metabolism, which is closely related to the occurrence of adult osteoporosis.The rapid growth and development in childhood is a period of extremely vigorous bone metabolism.The role of VK in children′s bone metabolic diseases has been gradually recognized in recent years.However, there are still few clinical studies on the level of VK in children of different ages and how VK participates in children′s bone metabolic diseases.This article reviews the types and metabolism of VK, the mechanism of VK regulating bone metabolism, the level of VK and its role in bone metabolic diseases, so as to provide new understanding and ideas for the prevention and treatment of bone health in children.
