Pathological Characteristics and Classification of Unstable Coronary Atheroscle-rotic Plaques
10.12116/j.issn.1004-5619.2022.421203
- VernacularTitle:不稳定冠状动脉粥样斑块病理特征及分类
- Author:
Yun-Hong XING
1
;
Yang LI
;
Wen-Zheng WANG
;
Liang-Liang WANG
;
Le-Le SUN
;
Qiu-Xiang DU
;
Jie CAO
;
Guang-Long HE
;
Jun-Hong SUN
Author Information
1. 山西医科大学法医学院,山西 晋中 030600
- Keywords:
forensic pathology;
sudden cardiac death;
coronary artery atherosclerotic heart disease;
athero-matous plaques;
pathological characteristics;
review
- From:
Journal of Forensic Medicine
2024;40(1):59-63
- CountryChina
- Language:Chinese
-
Abstract:
Important forensic diagnostic indicators of sudden death in coronary atherosclerotic heart dis-ease,such as acute or chronic myocardial ischemic changes,sometimes make it difficult to locate the ischemic site due to the short death process,the lack of tissue reaction time.In some cases,the de-ceased died of sudden death on the first-episode,resulting in difficulty for medical examiners to make an accurate diagnosis.However,clinical studies on coronary instability plaque revealed the key role of coronary spasm and thrombosis caused by their lesions in sudden coronary death process.This paper mainly summarizes the pathological characteristics of unstable coronary plaque based on clinical medi-cal research,including plaque rupture,plaque erosion and calcified nodules,as well as the influencing factors leading to plaque instability,and briefly describes the research progress and technique of the atherosclerotic plaques,in order to improve the study on the mechanism of sudden coronary death and improve the accuracy of the forensic diagnosis of sudden coronary death by diagnosing different patho-logic states of coronary atherosclerotic plaques.
