Surgical efficacy and prognostic factors for patients with advanced nasal and sinuses malignancies
10.16066/j.1672-7002.2023.12.001
- VernacularTitle:晚期鼻腔鼻窦恶性肿瘤手术疗效及预后因素研究
- Author:
Haixia XU
1
;
Yunfei BAI
;
Boqian WANG
;
Jiarong LIU
;
Xin LI
Author Information
1. 内蒙古医科大学附属医院耳鼻咽喉头颈外科,内蒙古 呼和浩特 010050
- Keywords:
Nasal Cavity;
Paranasal Sinus Neoplasms;
Surgical Procedures,Operative;
Prognosis
- From:
Chinese Archives of Otolaryngology-Head and Neck Surgery
2023;30(12):749-752
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate the surgical efficacy and prognostic factors of patients with advanced nasal and sinuses malignancies,in order to provide more reference for surgical plan selection and prognosis evaluation.METHODS A total of 117 patients with advanced nasal and sinuses malignancies were retrospectively chosen in the period from January 2010 to January 2019 in our hospital.The clinical characteristics and follow-up survival data were analyzed,and the independent prognostic factors of advanced nasal and paranasal malignant tumors were evaluated by univariate and multivariate methods.RESULTS The progression free survival rate and overall survival rate were 48.71%and 62.39%,respectively.The median progression free survival time and overall survival time were 32.48 months and 39.80 months,respectively.Univariate and multivariate analysis showed that age,histopathological type,marginal status and whether adjuvant therapy was accepted were independent factors influencing progression free survival time and overall survival time after surgery for advanced nasal and sinus malignancies(P<0.05).CONCLUSION The surgical efficacy of advanced nasal and sinusoidal malignancies is satisfactory and the clinical prognosis is related to age,marginal status and adjuvant therapy.