Clinical characteristics of 13 cases of organizing pneumonia secondary to invasive pulmonary aspergillosis
10.3969/j.issn.1671-8348.2024.05.019
- VernacularTitle:13例侵袭性肺曲霉菌病继发机化性肺炎的临床特征分析
- Author:
Shunxin ZHAO
1
;
Nan WANG
;
Liqun YE
;
Hongmin WANG
Author Information
1. 郑州大学第一附属医院呼吸内科,郑州 450052
- Keywords:
invasive pulmonary aspergillosis;
organizing pneumonia;
glucocorticoid
- From:
Chongqing Medicine
2024;53(5):745-747,753
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the clinical characteristics of organizing pneumonia secondary to inva-sive pulmonary aspergillosis.Methods A total of 13 patients with organizing pneumonia secondary to invasive pulmonary aspergillosis in the Department of Respiratory,the First Affiliated Hospital of Zhengzhou Univer-sity diagnosed by pathology from January 2019 to January 2021 were retrospectively included,and their clinical characteristics,laboratory examination,imaging characteristics,treatment and prognosis were comprehensively analyzed.Results Most cases of pulmonary aspergillosis occurred within 2-3 weeks of diagnosis,with coug-hing,expectoration,fever,and elevated C-reactive protein and erythrocyte sedimentation rate.Chest computed tomography showed patchy shadows around the original infection focus,mostly accompanied by consolidation,halo sign,bronchial inflation sign,and might be accompanied by cavity and pleural effusion;secondary multi lobed involvement of both lungs was observed,mostly with small patchy shadows,nodular shadows,and tree bud signs.After receiving glucocorticoid treatment,the symptoms were controlled within one week,and the glucocorticoid treatment course was mostly 3-6 months.Conclusion The clinical characteristics of organi-zing pneumonia secondary to invasive pulmonary aspergillosis are somewhat similar to those of cryptogenic or-ganizing pneumonia and have a better prognosis.
