Effect of lumbar bone marrow composition on bone marrow diffusion signal intensity and apparent diffusion coefficient in healthy adult women
10.3969/j.issn.1671-8348.2024.04.015
- VernacularTitle:健康成年女性腰椎骨髓成分对DWI骨髓扩散信号强度及ADC值的影响
- Author:
Zheng HAN
1
;
Liang HU
;
Jiangfeng PAN
;
Xiumei XIA
Author Information
1. 金华市中心医院医学影像科,浙江金华 321000
- Keywords:
lumbar bone marrow;
diffusion-weighted imaging;
age;
fat fraction;
menstrual status
- From:
Chongqing Medicine
2024;53(4):555-559
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the effect of lumbar bone marrow composition on bone marrow diffu-sion-weighted imaging(DWI)in healthy adult women.Methods Retrospective analysis was performed on up-per abdominal MRI of 103 adult women.Bone marrow fat fraction of lumbar vertebra was measured according to two-point water-lipid separation technique,and apparent diffusion coefficient(ADC)value of lumbar verte-bra was measured according to DWI image(b=800 s/mm2).The subjects were divided into the high-signal group and the equal-low-signal group according to the signal intensity of lumbar vertebra and adjacent erector spine muscles.The effects of age,lumbar bone marrow fat fraction and menstrual status on the signal intensity and ADC value of lumbar bone marrow diffusion were analyzed.Finally,the correlation between lumbar bone marrow fat fraction and ADC value was analyzed.Results Univariate analysis showed that the lumbar bone marrow diffusion signal intensity and ADC value were affected by age,lumbar bone marrow fat fraction and menstrual status(P＜0.001).Multivariate analysis showed that age(P=0.046)and lumbar bone marrow fat fraction(P=0.005)were the influencing factors of lumbar bone marrow diffusion signal intensity,but men-strual status(P=0.242)was not the influencing factor.In addition,lumbar bone marrow fat fraction(P＜0.001)was the factor influencing the ADC value of lumbar bone marrow,and the two were negatively correla-ted(r=-0.607,P＜0.001),but age(P=0.497)and menstrual status(P=0.082)were not the influencing factors.Conclusion The bone marrow composition of lumbar vertebrae in healthy adult women has significant effects on the signal intensity and ADC value of bone marrow diffusion.
