Research progress of Notch1/Jagged1 signaling pathway in related pathogenesis of chronic heart failure immune inflammation
10.3969/j.issn.1671-8348.2024.02.024
- VernacularTitle:Notch1/Jagged1信号通路在慢性心力衰竭免疫炎症相关发病机制中的研究进展
- Author:
Lian XU
1
,
2
;
Ghuangtong ZHUANG
;
Yalu QIN
;
Kunyuan YANG
Author Information
1. 成都中医药大学,四川 610075
2. 成都中医药大学附属第三医院/第三临床医学院/成都市郫都区中医医院心血管病科,四川 611730
- Keywords:
Notch1;
Jagged1;
chronic heart failure;
inflammatory response;
proinflammatory cytokine;
review
- From:
Chongqing Medicine
2024;53(2):291-296
- CountryChina
- Language:Chinese
-
Abstract:
Heart failure is a clinical syndrome caused by various causes of myocardial damage and cardi-ac function decrease that cannot meet the body's metabolic needs.The proinflammatory cytokines play an im-portant role in the process of occurrence and development of heart failure.The Notch1/Jagged1 signaling path-way is related to the proinflammatory cytokines,inflammatory responses and immune responses.This paper discusses the involvement of the Notch1/Jagged1 signaling pathway in the development and development of chronic heart failure by modulating immune inflammation.
