Comparison on effects among different modes of cardiac resynchronization therapy
10.3969/j.issn.1671-8348.2024.02.011
- VernacularTitle:不同方式的心脏再同步化治疗效果比较
- Author:
Shanshan HE
1
;
Jinrui GUO
;
Yulong GUO
;
Xiang CAI
;
Ke LIU
;
Guochun LI
;
Tao GUO
Author Information
1. 昆明医科大学附属心血管病医院心律失常中心,昆明 650000
- Keywords:
left bundle branch;
regional optimization;
cardiac resynchronization therapy;
biventricular pacing;
heart failure;
complete left bundle branch block
- From:
Chongqing Medicine
2024;53(2):214-219
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the application effects of cardiac resynchronization therapy(CRT)of[left bundle optimization(LOT)]and biventricular pacing(BiV)in the patients with chronic heart failure complicating left bundle branch block.Methods The single center,prospective and non-randomized controlled study method was used.Forty-two patients with heart failure meeting CRT in this center from April 2020 to April 2022 were consecutively included.Among them,32 cases adopted the BiV-CRT(BiV-CRT group)and 10 cases adopted LOT-CRT(LOT-CRT group).The pacing-making parameters,quality of life scale(SF-36)score,6-min walk test(6-MWT),ECG QRS width(QRSd),left ventricular end-diastolic diameter(LVEDD),left ventricular ejection fraction(LVEF)and New York cardiac function grade(NYHA)situation were collected before surgery,after surgery immediately and in postoperative 3,6,12 months.Their complica-tions and clinical outcomes were evaluated.Results The pacing threshold value in the LOT-CRT group was stable and lower than that in the BiV-CRT group(P＜0.05);QRSd in postoperative 12 months in the LOT-CRT group was shorter than that in the BiV-CRT group[(115.0±14.3)ms vs.(133.0±14.0)ms,P＜0.05]and 6-MWT was longer than that in the BiV-CRT group[(327.0±52.8)m vs.(274.0±52.8)m,P＜0.05],and the differences were statistically significant(P＜0.05);LVEF,LVEDD,NYHA cardiac grade and SF-36 score in postoperative 12 months were improved compared with those before implantation.The rehospitaliza-tion rate of heart failure in the LOT-CRT group was lower.Conclusion LOT-CRT could obtain a narrower QRS wave and longer 6-MWT than BiV-CRT.
