Capacity of decision-making under ambiguity in adult patients with moyamoya disease
10.19405/j.cnki.issn1000-1492.2023.12.021
- VernacularTitle:成年烟雾病患者的模糊决策功能研究
- Author:
Pan WU
1
;
Jiajia NIE
;
Yuxing HAO
;
Chao LI
;
Kai WANG
;
Ling WEI
Author Information
1. 安徽医科大学第一附属医院神经内科,合肥 230022
- Keywords:
moyamoya disease;
decision-making under ambiguity;
executive function;
cerebrovascular disease;
I-owa gambling task
- From:
Acta Universitatis Medicinalis Anhui
2023;58(12):2124-2128
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore whether the capacity of decision-making under ambiguity in adult patients with moyamoya disease(MMD)is impaired and its association with executive function.Methods Neuropsychological scales were used to measure the executive function of forty-one adult patients with MMD and forty-one healthy con-trols(HC),The Iowa Gambling Task(IGT)was utilized to study the capacity of decision-making under ambiguity of the two groups.Correlation analysis was performed between the two types of data.Results ① The total number of favorable choices in the MMD group was significantly lower than that in the HC group,with a statistically signifi-cant difference(Z=-2.782,P<0.01),and the total number of unfavorable choices was significantly higher than that of the controls,with a statistically significant difference(Z=-2.782,P<0.01).The results of ANOVA showed that the net residual value of Block4 and Block5 in MMD group was lower than that of Block4 and Block5 in HC group,respectively,and the differences were statistically significant(t=-3.433,P=0.001;t=-5.271,P<0.001),the net residual value of Block 1 was higher than that of Block 1 in HC group,the difference was statisti-cally significant(t=2.715,P=0.008).② Spearman correlation analysis revealed no association between the net score of IGT,the total number of favorable choices,the total number of unfavorable choices,and executive func-tion.Conclusion The capacity of decision-making under ambiguity in adult patients with MMD is impaired possi-bly,which is not correlated with executive cognition.