Study of glycosides from Piper sintenense Hatusima
10.11665/j.issn.1000-5048.2023122704
- VernacularTitle:小叶爬崖香中苷类化合物的研究
- Author:
Penghuang TU
1
;
Zhiren YAO
;
Meiling JIN
;
Guanyu NING
;
Yaping HUANG
;
Ke PAN
;
Zhiqi YIN
Author Information
1. 中国药科大学中药学院中药制药系
- Publication Type:Journal Article
- Keywords:
Piper spp. / Piper sintenense Hatusima / chemical constituents / glycoside / isolation and identification
- From:
Journal of China Pharmaceutical University
2024;55(2):202-208
- CountryChina
- Language:Chinese
-
Abstract:
In order to investigate the chemical constituents of glycosides in Piper sintenense Hatusima, column chromatographic techniques such as silica gel, ODS, MCI GEL CHP20P, Sephadex LH-20, and semi-preparative high performance liquid chromatography were used to afford nine glycosides from the n-butanol part of the 95% ethanol extract of Piper sintenense Hatusima. Based on the physicochemical properties and NMR data, the above compounds were identified as (2S)-2-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone-2-O-β-D-glucopyranoside (1), 2-phenylethyl β-D-glucopyranoside (2), benzyl α-L-arabinopyranosyl-(1''→6')-β-D-glucopyranoside (3), benzyl β-D-xylopyanosyl-(1''→6')-β-D-glucopyranoside (4), phenethyl β-D-apiofuranosyl-(1''→ 2')-β-D-glucopyranoside(5), salidroside (6), phenethanol β-D-xylopyanosyl-(1''→6')-β-D-glucopyranoside (7), (Z)-hexenyl-O-α-L-arabinopyranosyl-(1''→6')-O-β-D-glucopyranoside (8), (Z)-hexenyl-O-β-D-xylopyanosyl-(1''→6')-O-β-D-glucopyranoside (9). Compound 1 was identified as a new compound, and compounds 3-9 were isolated from the genus Piper for the first time.
