Ovarian carcinosarcoma with Yolk Sac Tumor in a post-menopausal female: A case report and review of literature
https://doi.org/10.21141/PJP.2021.18
- Author:
Margarita Rae Rosario
1
;
Jeffrey So
1
;
Claire Anne Therese Hemedez
1
;
Carlos Dy
2
Author Information
1. Institute of Pathology, St. Lukes Medical Center, Quezon City, Philippines
2. Cancer Institute, St. Lukes Medical Center, Quezon City, Philippines
- Publication Type:Journal Article
- Keywords:
Postmenopausal
- MeSH:
Carcinosarcoma;
Endodermal Sinus Tumor;
Ovary
- From:
Philippine Journal of Pathology
2021;6(2):59-65
- CountryPhilippines
- Language:English
-
Abstract:
Yolk sac tumor is the second most common subtype of ovarian germ cell tumors and is rare in postmenopausal women. The few cases in literature have found that in this age group, yolk sac tumors more commonly present as a mixed component, combined with epithelial tumors. We report a case of a 60-year-old female who presented with an enlarging abdominopelvic mass. Imaging pointed to an ovarian new growth. Total abdominal hysterectomy with bilateral salpingo-oophorectomy revealed a tumor with three populations composed of carcinomatous, sarcomatous, and germ cell components, which was ultimately diagnosed as an ovarian carcinosarcoma with concurrent yolk sac tumor based on histomorphology and immunohistochemical staining. This report also discusses the proposed pathogenesis, treatment, and prognosis of this uncommon entity.
- Full text:47 pjp.pdf
