- Author:
John Nicholas Pantoja
1
;
Francisco Tria IV
1
;
Manuelito Madrid
1
Author Information
- Publication Type:Case Reports
- Keywords: Secretory carcinoma; Submandibular gland mass; ETV6-NTRK3 fusion; School-age child
- From: Philippine Journal of Pathology 2022;7(2):46-49
- CountryPhilippines
- Language:English
- Abstract: Secretory carcinoma is a recently described salivary gland neoplasm reported in the fourth edition of World Health Organization classification of head and neck tumors.1 We report a case of a primary secretory carcinoma arising from the submandibular gland that was completely excised in a 10-year-old. The histomorphologic features and the immunophenotype studies are compatible with secretory carcinoma. Unless proven otherwise by immunohistochemical stains and cytogenetics, secretory carcinoma should be included as a differential in cases of lesion of the major and minor salivary glands that has the primary differential diagnosis of acinic cell carcinoma. This case report aims to contribute to the limited literature about this disease entity and would be one of the few reported cases of the disease in a school-age child.
- Full text:25 pjp.pdf