Long-term Epidemiological and etiological characteristics of hand foot mouth disease in Huai'an , Jiangsu Province , 2009 -2022
10.3969/j.issn.1006-2483.2024.03.010
- VernacularTitle:2009—2022年江苏省淮安市手足口病长期流行特征及病原监测分析
- Author:
Lei XU
1
,
2
,
3
;
Qiang GAO
1
,
2
,
3
;
Yongli CAI
4
,
5
;
Liyun YANG
1
,
2
,
3
;
Li TANG
1
,
2
,
3
;
Fang HE
1
,
2
,
3
Author Information
1. Huai'
2. an Center for Disease Control and Prevention , Huai'
3. an , Jiangsu 223003 , China
4. Huaiyin Normal University , Huai'
5. an , Jiangsu 223001, China
- Publication Type:Journal Article
- Keywords:
Hand, foot and mouth disease;
Enterovirus;
Coxsackievirus;
Epidemiological features;
Etiological surveillance
- From:
Journal of Public Health and Preventive Medicine
2024;35(3):41-45
- CountryChina
- Language:Chinese
-
Abstract:
Objective The long-term epidemiological and etiological characteristics of hand, foot and mouth disease (HFMD) in Huai’an, Jiangsu were analyzed to provide scientific evidence for the prevention of HFMD. Methods The data of HFMD reports, etiological diagnosis and in Huai’an from 2009 to 2022 were described and analyzed. Results A total of 78 535 cases were reported from 2009 to 2022 , with 14-year average annual incidence rate of 114.71/100 000. Before 2020, the incidence rate of HFMD in Huai’an showed the epidemic intensity increased every other year on the whole, and the average annual incidence rate during the COVID-19 pandemic (2020-2022) (55.69/100 000) was significantly lower than that in previous years (2009-2019) (129.95/100 000). The joinpoint regression analysis showed that the best fitting model from 2009 to 2022 had no joinpoints, APC=AAPC=-1.24%. The overall trend showed a monotonously decreasing trend, but the trend was not statistically significant. The male-to-female distribution ratio was 1.53:1, and the age distribution was mainly under 5 years old, especially in scattered children. The epidemic season was from April to July. The results of etiological surveillance showed that the co-epidemic of Coxsackievirus A16 (CV-A16) and Enterovirus A71 (EV-A71) during the early stages had changed to the co-epidemic of CV-A16 and CV-A6 in the current period. Conclusion The burden of HFMD in Huai’an was large, and the epidemic intensity increased every other year was affected by the COVID-19 pandemic. The epidemiological features after the COVID-19 pandemic should be further monitored.
