Hepatitis E virus infection in liver transplant recipients
10.3969/j.issn.1674-7445.2023216
- VernacularTitle:肝移植受者戊型肝炎病毒感染
- Author:
Fansheng GUO
1
;
Qiang ZENG
1
;
Jian DOU
1
Author Information
1. Department of Hepatobiliary Surgery, Hebei Medical University Third Hospital, Shijiazhuang 050051, China.
- Publication Type:Editorial
- Keywords:
Hepatitis E virus;
Liver transplantation;
Epidemiological characteristics;
Chronic hepatitis E;
Liver fibrosis;
Cirrhosis;
Ribavirin;
Sustained virological response
- From:
Organ Transplantation
2024;15(3):352-358
- CountryChina
- Language:Chinese
-
Abstract:
Hepatitis E virus infection is a common cause of acute viral hepatitis. In recent years, the incidence of hepatitis E has shown an increasing trend, which has gradually become an important cause of acute viral hepatitis worldwide. Age, sex, intensity of immunosuppression and socio-economic factors are all risk factors for hepatitis E virus infection. Liver transplant recipients require long-term use of immunosuppressive drugs for anti rejection treatment, prone to hepatitis E virus infection and at the risk of liver fibrosis and cirrhosis due to immunosuppression status. Therefore, special attention should be paid to liver transplant recipients in clinical practice. Meantime, related risk factors should be identified to assist diagnosis and take stricter preventive measures. According to literature review, the etiological characteristics of hepatitis E virus and the epidemiological characteristics, clinical manifestations, diagnosis and treatment of hepatitis E virus infection in liver transplant recipients were reviewed, aiming to properly monitor, treat and prevent hepatitis E virus infection in liver transplant recipients in clinical practice, improving the prognosis of liver transplant recipients.
