Research Progress in Mitochondrial Treatment and Mechanism in Occurrence of Lung Cancer

VernacularTitle:线粒体在肺癌发生中的作用机制及治疗研究进展
Author: Fasheng WU ¹ ; Hui ZHANG ; Jiatong XIE ; Jianfu LI ; Hui CHEN ; Shijin LU
Author Information

1. Department of Radiotherapy, Ruikang Hospital, Guangxi University of Chinese Medicine, Nanning 530011, China
Publication Type:Research Article
Keywords: Mitochondria; Lung cancer; Mechanism; Treatment
From: Cancer Research on Prevention and Treatment 2024;51(4):278-283
CountryChina
Language:Chinese
Abstract: Lung cancer is characterized by high incidence and mortality rates and invasiveness, and its occurrence and development are influenced by various factors. Mitochondria, as ubiquitous organelles in the human body, regulate cellular processes, such as metabolism, signal transduction, oxidative stress, and genomic instability, thereby affecting the initiation and progression of lung cancer. This article summarizes the recent research progress on mitochondrial-targeted drugs, mitochondrial transfer, and mitochondrial gene therapy for lung cancer treatment. This work also discusses the principles and prospects of mitochondrial therapy to provide new insights for lung cancer treatment.