Drug therapy analysis and care on a patient with Lemierre’s syndrome
- VernacularTitle:1例Lemierre’s综合征患者的药物治疗分析与监护
- Author:
Yusi LIU
1
;
Lingfeng HUANG
2
;
Qinmiao HUANG
2
;
Weiling CAO
1
;
Peng ZHANG
1
Author Information
1. Dept. of Pharmacy，Shenzhen Luohu District People’s Hospital，Guangdong Shenzhen 518000，China
2. Dept. of Respiratory Medicine，Shenzhen Luohu District People’s Hospital，Guangdong Shenzhen 518000，China
- Publication Type:Journal Article
- Keywords:
Lemierre’s syndrome;
mNGS;
Fusobacterium necrophorum;
clinical pharmacist;
pharmaceutical care
- From:
China Pharmacy
2024;35(8):997-1000
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To provide a reference for the early diagnosis， drug treatment and medication monitoring for patients with Lemierre’s syndrome. METHODS The doctors confirmed the diagnosis of the patient as having Lemierre’s syndrome based on the patient’s condition and the results of metagenomic next-generation sequencing （mNGS）， and the clinical pharmacists participated in the treatment process of the patient. During the treatment process， the clinical pharmacists suggested using piperacillin sodium and tazobactam sodium combined with metronidazole for anti-infective treatment against Fusobacterium necrophorum infection； clinical pharmacists recommend anticoagulant treatment with Enoxaparin sodium injection for left internal jugular vein thrombophlebitis. RESULTS The doctors accepted the suggestion of the clinical pharmacists， and the patient’s condition improved after treatment and was allowed to be discharged with medication. CONCLUSIONS By interpreting the results of mNGS， combined with the patient’s condition， the clinical pharmacists assist doctors in formulating individualized anti-infective and anticoagulant plans for the patient and provide medication monitoring， ensuring the safety and effectiveness of the patient’s medication.
