Serum ferritin and PELOD-2 scores in Critically Ill Septic Children - A cross-sectional single-center study
https://actamedicaphilippina.upm.edu.ph/index.php/acta/article/view/6496/4762
- Author:
Gema Nazri Yanni
1
;
Rina Amalia C. Saragih
1
;
Aridamuriany Dwiputri Lubis
1
Author Information
1. Department of Pediatrics, Faculty of Medicine, Universitas Sumatera Utara
- Publication Type:Journal Article
- Keywords:
PELOD-2
- MeSH:
Ferritins;
Sepsis;
Infections
- From:
Acta Medica Philippina
2024;58(6):64-68
- CountryPhilippines
- Language:English
-
Abstract:
Objective:This study aims to assess the correlation of ferritin serum level and PELOD-2 score, and determine the effectiveness of ferritin serum level as early indicator of organ dysfunction.
Methods:This was a cross-sectional study carried out to pediatric patients with sepsis in the Pediatric Intensive Care Unit Haji Adam Malik and Universitas Sumatera Utara hospital from June 2021 – January 2022. Complete blood work was done, and ferritin serum level and PELOD-2 score were measured on the first and third day of hospital stay of all the sixty participants aged 1-18 years old with sepsis. The correlation was measured using Spearman test, with p<0.05 indicating a significant correlation.
Results:The median level of serum ferritin level was 480 (24.7 – 22652) ng/mL. There were 20% patients with ferritin level <200 ng/mL, 26.7% with ferritin level 200-500 ng/mL, and 53.3% patients with ferritin >500 ng/mL. The median score of PELOD-2 was 4. There was a significant correlation of serum ferritin and PELOD-2 score on day 1 of hospital stay.
Conclusion:The ferritin serum level is effective as an early indicator of organ dysfunction until PELOD-2 score is established. There is a positive correlation between serum ferritin and PELOD-2 score. There is a link between elevated ferritin and worse disease prognosis.
- Full text:6496-Article Text-109879-3-10-20240415.pdf
