Mechanism and prevention of liver failure complicated by acute pancreatitis

VernacularTitle:肝衰竭并发急性胰腺炎的机制及预防
Author: Xingyu LU ¹ ; Jing YANG ¹ ; Pan LI ¹ ; Jianping PENG ¹
Author Information

1. Department of Hepatology， The First Affiliated Hospital of Hunan University of Chinese Medicine， Changsha 410000， China
Publication Type:Review
Keywords: Liver Failure; Pancreatitis， Acute Necrotizing; Pathologic Processes; Early Medical Intervention
From: Journal of Clinical Hepatology 2024;40(4):850-856
CountryChina
Language:Chinese
Abstract: Liver failure often has rapid progression， multiple complications， and dangerous conditions. Acute pancreatitis is a common comorbidity during the progression of liver failure， and since acute pancreatitis has extremely similar clinical symptoms and signs to liver failure complicated by spontaneous peritonitis， it is often neglected in clinical practice. This article elaborates on the mechanisms of liver failure complicated by acute pancreatitis from the five aspects of inflammatory response， duodenal papillary dysfunction， gut microbiota dysbiosis， oxidative stress， and microcirculatory disturbance and proposes corresponding preventive measures based on these mechanisms.