Mechanism of action of traditional Chinese medicine in treatment of nonalcoholic fatty liver disease based on intestinal microecology

VernacularTitle:基于肠道微生态探讨中医药治疗非酒精性脂肪性肝病的作用机制
Author: Xue YANG ¹ ; Xu ZHANG ¹ ; Jin XIAN ² ; Qiwen TAN ² ; Huijuan YU ²
Author Information

1. School of Acupuncture and Massage， Shandong University of Traditional Chinese Medicine， Jinan 250014， China
2. Preventive Treatment Center， The Affiliated Hospital of Shandong University of Traditional Chinese Medicine， Jinan 250014， China
Publication Type:Review
Keywords: Non-alcoholic Fatty Liver Disease; Gut Microbiota; TCM Therapy
From: Journal of Clinical Hepatology 2024;40(4):804-809
CountryChina
Language:Chinese
Abstract: Nonalcoholic fatty liver disease （NAFLD） is a multisystem disease associated with obesity， insulin resistance， and dyslipidemia and has a complex pathogenesis. Studies have shown that gut microbiota dysbiosis is closely associated with the onset of NAFLD， and traditional Chinese medicine treatment can improve the laboratory markers and clinical symptoms of NAFLD patients by regulating intestinal microbiota and its metabolites. This article elaborates on the association between NAFLD and gut microbiota， the involvement of gut microbiota dysbiosis in the pathogenesis of NAFLD， and the possible mechanism of traditional Chinese medicine treatment in improving NAFLD from the perspective of gut microbiota， in order to provide new ideas for the treatment of NAFLD.