Characteristics of cases with enterovirus-D68 infectionsin the respiratory tract
10.19485/j.cnki.issn2096-5087.2024.01.011
- Author:
JIANG Zhuojing
;
HUANG Zemin
;
WANG Jiling
;
CHEN Jinkun
- Publication Type:Journal Article
- Keywords:
enterovirus-D68;
respiratory tract infection;
genotype;
etiological surveillance
- From:
Journal of Preventive Medicine
2024;36(1):44-46
- CountryChina
- Language:Chinese
-
Abstract:
Objective :To investigate the clinical and molecular epidemiological characteristics of 10 patients with enterovirus (EV)-D68 infections in the respiratory tract in Shaoxing City, Zhejiang Province, so as to provide insights into formulation of control interventions for EV-D68 infections.
Methods:Clinical specimens were sampled from patients with acute respiratory tract infections (ARTIs) admitted to sentinel hospitals in Shaoxing City from 2021 to 2022, and EV-D68 was detected using real-time fluorescent PCR assay and sequencing of the VP1 region of enterovirus. The epidemiological and etiological characteristics of EV-D68 infected cases were descriptively analyzed.
Results:A total of 3 009 specimens were sampled from patients with ARTIs from 2021 to 2022, and the detection of EV-D68 was 0.33%. Of all EV-D68-infected patients, there were 6 men and 4 women, and 5 cases under 18 years of age, 2 cases at ages of 18 to 60 years and 3 cases at ages of over 60 years. EV-D68 infection predominantly occurred in summer (5 cases detected between May and July) and autumn (5 cases detected between September and October). The main clinical symptoms included fever (10 cases), sore throat (9 cases) and cough (8 cases), and all 10 cases recovered well, with no deaths reported. Sequencing identified D3 subtype in all 10 specimens positive for EV-D68.
Conclusions:The ARTIs caused by EV-D68 occurred predominantly among children under 18 years of age in Shaoxing City, and was highly prevalent in summer and autumn. D3 was the predominant enterovirus subtype.
- Full text:呼吸道感染肠道病毒D68型病例特征分析.pdf
