Modified Fixation of Levonorgestrel-releasing Intrauterine System for the Treatment of Adenomyosis
10.13471/j.cnki.j.sun.yat-sen.univ（med.sci）.20240314.001
- VernacularTitle:改良式左炔诺孕酮宫内缓释系统固定治疗子宫腺肌病
- Author:
Jinbo LI
1
;
Xueyun LI
2
;
Fuli WU
3
;
Shuqin CHEN
1
Author Information
1. Department of Gynecology, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou 510655, China
2. Department of Gynecology and Obstetrics, The Third People's Hospital of Shunde District, Foshan 528300, China
3. Department of Gynecology, Yuexi Hospital of the Sixth Affiliated Hospital, Sun Yat-sen University //Xinyi People's Hospital, Maoming 525300, China
- Publication Type:Journal Article
- Keywords:
levonorgestrel-releasing intrauterine system （LNG-IUS）;
adenomyosis;
modified fixation;
menorrhagia;
dysmenorrhea
- From:
Journal of Sun Yat-sen University(Medical Sciences)
2024;45(2):290-296
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo introduce a fixation technique with the modified levonorgestrel-releasing intrauterine system （LNG-IUS） and evaluate its efficacy in the treatment of adenomyosis patients with previous LNG-IUS expulsion. MethodsA retrospective analysis was done on 22 adenomyosis patients who underwent modified LNG-IUS fixation due to LNG-IUS expulsion at three hospitals from June 2022 to June 2023. The baseline clinical characteristics， operative and postoperative details were collected and analyzed. The Visual analogu scale （VAS） scores and pictorial blood loss assessment chart （PBAC） scores were measured and compared before， 3 and 6 months after the LNG-IUS fixation. ResultsThe mean operative time was （19.51±7.41） min and intraoperative bleeding was （6.71±5.30） mL. Of the patients， 13 were operated under local anaesthesia and the other 9 under intravenous anaesthesia. There were 4 operations performed by a resident doctor， 15 by an attending doctor and 3 by a senior doctor. No intraoperative or postoperative complication was found. The mean follow-up was 11.51 months and no patient had a recurrence of LNG-IUS expulsion during the follow-up period. The mean level of hemoglobin at 1 month after operation was significantly higher than that before （P<0.001）. VAS scores and PBAC scores at 3 and 6 months postoperatively were all improved significantly than those preoperatively （P<0.001）. ConclusionsEffectively preventing the recurrence of LNG-IUS expulsion， modified LNG-IUS fixation is a safe and efficient method for adenomyosis patients with previous LNG-IUS expulsion. Modified LNG-IUS fixation deserves the clinical application due to its easy operation and wide range of use on women.
