Status risk factors and prevention and control strategies of familial aggregation of Helicobacter pylori infection
10.3969/j.issn.1006-2483.2024.04.034
- VernacularTitle:幽门螺杆菌家庭聚集性感染及其防控策略
- Author:
Lihua SONG
1
;
Sijing HAN
1
;
Shuqin REN
1
;
Wen YANG
1
;
Sihong DING
1
;
Yixin ZHONG
1
;
Yao QIN
1
;
Huiyue ZHANG
1
;
Yang ZHANG
1
Author Information
1. Department of Gastroenterology , the 2nd Affiluated Hospital of Chengdu Medical College Nuclear Industry 416 Hospital ,Chengdu , Sichuan 610051 , China
- Publication Type:Journal Article
- Keywords:
Helicobacter pylori infection;
Family aggregation infection;
Prevention and control strategies
- From:
Journal of Public Health and Preventive Medicine
2024;35(2):148-151
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the status of familial aggregation of Helicobacter pylori (Hp) infection in Jinniu District, Chengdu, and analyze its risk factors so as to provide a basis for developing prevention and control strategies of family aggregation of Hp infection. Methods A total of 172 subjects in the Second Affiliated Hospital of Chengdu Medical College · 416 Hospital of Nuclear Industry from January 2022 to January 2023 were selected as the research subjects. All subjects underwent 13C-urea breath test (13C-UBT) to diagnose whether there was Hp infection. Analyze the current situation of family aggregation of Hp infection in the region, collect general data of survey subjects, analyze the relevant factors affecting Hp family aggregation infection, and develop prevention and control strategies based on this. Results A total of 242 people from 97 households were surveyed, and the Hp family aggregation rate was 29.33%. Univariate analysis showed that there were statistically significant differences in family aggregation of Hp infection in terms of different age groups (χ2=9.719, P=0.008), marital status (χ2=8.496, P=0.014), occupations (χ2=19.462, P<0.001), frequencies of dining out (χ2=5.457, P=0.019), previous Hp test results (χ2 =4.131, P=0.042) and test results after treatment (χ2=12.000, P=0.001), with statistical significance (P<0.05). Multivariate logistic regression analysis showed that the frequency of dining out 2 days or more per week and a positive Hp test results in the past were risk factors for family aggregation of Hp infection, while the occupation of teachers/medical staff/management/technology personnel and a negative Hp results after treatment were protective factors (P<0.05). Conclusion Family aggregation of Hp infection is related to family members' occupation, frequency of dining out, previous Hp test results and Hp test results after eradication, which deserves attention in clinical practice.
