Correlation between 23 metals and metalloids elements in the urine and thyroid function of traffic police
10.3969/j.issn.1006-2483.2024.02.006
- VernacularTitle:交通警察尿液中23种金属和类金属元素与甲状腺功能的关联性分析
- Author:
Yaru WANG
1
;
Chao QUAN
1
;
Tian XYU
2
;
Shuxia LIU
1
;
Lizhao YANG
1
;
Ling ZHANG
1
;
Xiayun DAI
2
Author Information
1. Wuhan University of Science and Technology , Wuhan , Hubei 430065 , China
2. Wuhan Prevention and Treatment Center for Occupational Diseases , Wuhan , Hubei 430015 , China
- Publication Type:Journal Article
- Keywords:
Traffic police;
Metals and metalloids elements;
Thyroid function
- From:
Journal of Public Health and Preventive Medicine
2024;35(2):25-29
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation between 23 metals and metalloids elements in the urine and thyroid function indicators in the blood of traffic police. Methods A cross-sectional study was performed to assess the effects of 23 metals and metalloids elements in the urine on blood thyroid function indicators in 166 traffic policemen (122 field staff and 44 internal staff) in Wuhan, Hubei Province. Each subject received an occupational health examination. Results After multiple corrections for false detection rates, in the polymetallic model, the levels of urinary manganese and urinary uranium were positively correlated with the levels of thyroid peroxidase antibody (TPOAb) in the blood (β = 66.57, 95% CI 2.92-130.22, P = 0.040 and β = 62.43, 95% CI 14.37-110.49, P = 0.011), and the level of urinary uranium was positively correlated with thyroid stimulating hormone (TSH) levels in the blood (β = 6.20, 95% CI 2.68-9.72 , P = 0.001). Urinary uranium level was negatively correlated with free thyroxine level in the blood (FT4) (β = -2.03, 95 % CI (-3.67 )- (-0.39), P = 0.015), and urinary lead level was negatively correlated with blood TSH level (β = -4.59, 95% CI (-8.67) - (-0.51), P = 0.027). Conclusion Manganese exposure is related to the increase of TPOAb level in blood, uranium exposure is related to the increase of TPOAb and TSH levels and the decrease of FT4 level in blood, and lead exposure is related to the decrease of TSH level in blood, suggesting that more attention should be paid to the effects of heavy metals on the thyroid of traffic police.
