Association of short-term exposure to ambient PM1 with hospital admissions for angina in older adults
10.3969/j.issn.1006-2483.2024.02.002
- VernacularTitle:大气PM1短期暴露与老年人心绞痛住院的关联研究
- Author:
Luxi XU
1
,
2
;
Ruijun XYU
1
;
Yunshao YE
3
;
Qiaoxuan LIN
3
;
Hong SUN
4
;
Qi TIAN
3
;
Yuewei LIU
1
Author Information
1. Department of Epidemiology , School of Public Health , Sun Yat-sen University , Guangzhou , Guangdong 510080 , China
2. Institute of Environmental Health and Endemic Disease Control , Guangxi Zhuang Autonomous Region Center for Disease Control and Prevention , Nanning , Guangxi 530028 , China
3. Guangzhou Health Technology Identification & Human Resources Assessment Center , Guangzhou , Guangdong 510080 , China
4. Institute of Environment and Health , Jiangsu Provincial Center for Disease Control and Prevention , Nanjing , Jiangsu 210009 , China
- Publication Type:Journal Article
- Keywords:
Particulate matter;
Older adults;
Angina;
PM1;
Hospital admission
- From:
Journal of Public Health and Preventive Medicine
2024;35(2):6-11
- CountryChina
- Language:Chinese
-
Abstract:
Objective To quantitatively evaluate the association of short-term exposure to ambient submicron particulate matter (PM1) with hospital admissions for angina in older adults. Methods A case-crossover study was conducted among 46 687 older adults hospitalized for angina from 2016 to 2019 in Guangzhou medical institutions. Grid data on ambient PM1 concentrations in Guangzhou were obtained from the ChinaHighAirPollutants (CHAP) dataset. Exposure to PM1 was assessed according to each subject's residential addresses. Conditional logistic regression model was used to analyze the the exposure-response association between PM1 and hospital admissions for angina. Results From 2016 to 2019, the average exposure level of PM1 on the same day of hospital admissions (lag 0) for angina was 21.0 ± 11.5 μg/m3. The results of main model analysis showed that lag 0 day exposure to ambient PM1 was significantly associated with a higher odds of hospital admissions for angina in older adults. Each 10 μg/m3 increase of PM1 exposure level was significantly associated with a 1.31% (95% CI: 0.05%, 2.59%) increased odds of angina admissions. Results from a two-pollutant model adjusting for O3 showed that the association between short-term exposure to PM1 and odds of hospitalization for angina remained stable. According to the results of the above model, it was estimated that the excess hospitalization attributable to ambient PM1 exposure accounted for 2.46% (95% CI: 0.09%, 4.76%) of the total admissions in Guangzhou during 2016-2019, corresponding to 1539 (95% CI: 54, 2976) admissions. No significant effect modification on the associations was observed by sex, age, or season. Conclusion Short-term exposure to ambient PM1 was significantly associated with an increased odds of hospital admissions for angina in older adults.
